SpIntellx Inc. has been awarded a National Science Foundation (NSF) Small Business Innovation Research (SBIR) grant for $225,000 to conduct research and development (R&D) work on its HistoMapr-Breast product. HistoMapr-Breast is a computational guide for pathologists that automatically recognizes and classifies regions of interest in H&E-stained and/or immunohistochemistry slides and supports pathologists in improving the accuracy and efficiency of reading whole slide images. 

SpIntellx applies its proprietary explainable AI technologies to analyze whole slide image pathology samples based on spatial analytics for pathologists in all therapeutic areas. The company is developing a platform for transmitted light applications, HistoMaprTM, as well as for multiplexed to hyperplexed applications, TumorMaprTM.

“The National Science Foundation supports startups and small businesses with the most innovative, cutting-edge ideas that have the potential to become great commercial successes and make huge societal impacts,” said Graciela Narcho, acting director of Division of Industrial Innovation and Partnerships at NSF. “We hope that seed funding will spark solutions to some of the most important challenges of our time across all areas of science and technology.”

“The SpIntellx HistoMapr technology platform is applicable to a broad array of pathology disease areas, such as oncology, immunology and other chronic disorders,” said Dr. S. Chakra Chennubhotla, CEO and co-founder of SpIntellx Inc.

Once a small business is awarded a Phase I SBIR/STTR grant (up to $225,000), it becomes eligible to apply for a Phase II grant (up to $750,000). Small businesses with Phase II grants are eligible to receive up to $500,000 in additional matching funds with qualifying third-party investment or sales.

NSF accepts Phase I proposals from small businesses twice annually in June and December. Small businesses with innovative science and technology solutions, and commercial potential are encouraged to apply. All proposals submitted to the NSF SBIR/STTR program undergo a rigorous merit-based review process.